What are the most famous/important questions in the Bible?

GotQuestions.org

Question: “What are the most famous/important questions in the Bible?”

Answer: There are many, many questions in the Bible. It is difficult to give a precise number because ancient Hebrew and Koine Greek did not use punctuation—we can’t just pull out the Dead Sea Scrolls and count the question marks! Often, it is difficult to know if a sentence is truly intended to be a question. But Bible scholars estimate that there are approximately 3,300 questions in the Bible.
This list of questions in the Bible is definitely not complete. It is simply a survey of some of the most famous and important questions in the Bible…
 

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What are the most famous/important questions in the Bible?